Fig. 7

MiR-24-3p targeted CTSB to participate in IL-1β-induced chondrocyte injury. A Relative levels of CTSB protein in CHON-001 cells with or without IL-1β stimulation, as well as IL-1β-stimulated CHON-001 cells transfected with miR-NC, miR-24-3p, miR-24-3p+pcDNA, or miR-24-3p+CTSB. B–D Cell viability, proliferation, and apoptosis in the above-mentioned CHON-001 cells were determined. E Bcl-2 and Bax protein levels in the above-mentioned CHON-001 cells were assessed. F–H The production of IL-6, TNF-α, and MDA in the above-mentioned CHON-001 cells was measured. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001