Fig. 5

IL-1β induced chondrocyte injury via the circ_0020014/miR-24-3p axis. A RT-qPCR detection of miR-24-3p in CHON-001 cells with or without IL-1β stimulation, as well as IL-1β-stimulated CHON-001 cells transfected with si-NC, si-circ_0020014, si-circ_0020014+anti-miR-NC, or si-circ_0020014+anti-miR-24-3p. B–D Measurement of cell viability, proliferation, and apoptosis in the above-mentioned CHON-001 cells was done. E Analysis of Bcl-2 and Bax protein levels in the above-mentioned CHON-001 cells was done. F–H Detection of the levels of IL-6, TNF-α, and MDA in the above-mentioned CHON-001 cells was carried out. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001