Fig. 3

Circ_0020014 participated in IL-1β-prompted chondrocyte injury. A Relative expression of circ_0020014 in CHON-001 cells with or without IL-1β stimulation, as well as IL-1β-stimulated CHON-001 cells transfected with si-NC or si-circ_0020014. B–D Cell viability, proliferation, and apoptosis in the above CHON-001 cells were analyzed. E Relative protein levels of Bcl-2 and Bax in the above CHON-001 cells were detected. F–H The levels of IL-6, TNF-α, and MDA in the above CHON-001 cells were measured. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001