Fig. 2
Circ_0020014 expression was increased in OA patient-derived articular cartilages and IL-1β-stimulated chondrocytes. A and B Relative expression of circ_0020014 in articular cartilages from OA patients and normal controls, as well as CHON-001 cells treated with different doses of IL-1β. C Relative expression levels of circ_0020014 and linear GAPDH in total RNA derived from CHON-001 cells with or without RNase R treatment. D Relative expression levels of circ_0020014 and linear GAPDH were analyzed by RT-qPCR using random or oligo(dT)18 primers in reverse transcription experiments. E The proportion of circ_0020014 in the cytoplasm and nucleus of CHON-001 cells. **P < 0.01, ***P < 0.001, and ****P < 0.0001