Table 8 The mediation effect of CCI on the association between related variables and ICU requirement in patients with TAA
Exposure factors | Exposure to CCI | CCI to outcome | Total effect (exposure to outcome) | Direct effect | CCI-mediated effect |
|---|---|---|---|---|---|
Age | 0.080 (< 0.001) | − 0.038 (0.001) | − 0.003 (0.114) | 0.000 (0.990) | − 0.003 (< 0.001) |
RDW | 0.197 (< 0.001) | − 0.041 (0.002) | − 0.019 (0.130) | − 0.012 (0.361) | − 0.008 (0.032) |
Platelet | 0.002 (0.080) | − 0.041 (0.002) | − 0.001 (0.037) | − 0.001 (0.070) | 0.000 (0.308) |
Urea nitrogen | 0.050 (< 0.001) | − 0.040 (0.002) | − 0.003 (0.217) | − 0.001 (0.613) | − 0.002 (0.016) |
Creatinine | 0.355 (0.025) | − 0.039 (0.004) | − 0.023 (0.512) | − 0.010 (0.782) | − 0.014 (0.096) |