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Table 3 Risk factors for neuropathic pain in complete or incomplete SCI according to American Spinal Injury Association Impairment Scale: univariate logistic regression analysis

From: The impact of time from injury to surgery on the risk of neuropathic pain after traumatic spinal cord injury

 

AIS A grade

AIS B, C and D grade

Odds ratios

95% confidence interval

p value

Odds ratios

95% confidence interval

p value

Age (y)

  

0.576

  

0.703

 ≤ 40

–

–

 

–

–

 

41–60

0.684

(0.183, 2.548)

0.571

0.588

(0.170, 2.039)

0.403

 > 60

1.389

(0.282, 6.835)

0.686

0.603

(0.170, 2.138)

0.433

Sex

      

Male

1.344

(0.541, 3.340)

0.525

0.744

(0.410, 1.461)

0.430

Female

–

–

 

–

–

 

Age at injury (y)

  

0.037

  

0.012

 ≤ 40

–

–

 

–

–

 

41–60

0.556

(0.164, 1.883)

0.345

6.429

(1.420, 29.10)

0.016

 > 60

1.778

(0.483, 6.547)

0.387

9.462

(2.059, 43.48)

0.004

Time post-injury (y)

0.859

(0.825, 2.282)

0.625

1.153

(0.965, 1.282)

0.825

Body Mass Index(kg/m2)

      

 < 24

0.936

(0.953, 1.071)

0.863

0.800

(0.459, 1.395)

0.432

 ≥ 24

–

–

–

–

–

–

Current smoker

0.859

(0.466, 1.582)

0.744

1.004

(0.515, 1.959)

0.990

Highest level of education

  

0.825

  

0.098

Illiterate

1.158

(0.282, 4.749)

0.839

0.262

(0.065, 1.055)

0.060

Pre–high school

0.681

(0.254, 1.823)

0.445

0.960

(0.440, 2.095)

0.918

High school

0.891

(0.321, 2.468)

0.824

0.553

(0.274, 1.115)

0.098

College and above

–

–

–

–

–

–

Etiology

  

0.326

  

0.579

Falls

0.635

(0.145, 2.783)

0.547

1.302

(0.453, 3.742)

0.625

Traffic accident

1.136

(0.240, 5.390)

0.872

1.805

(0.615, 5.294)

0.282

Violence

0.300

(0.041, 2.200)

0.236

2.000

(0.366, 10.919)

0.423

Others

–

–

 

–

–

 

ISS

  

0.020

  

0.008

 < 16

–

–

 

–

–

 

 ≥ 16

2.525

(1.157, 5.507)

 

3.171

(1.350, 7.452)

 

Neurological level of injury

  

0.025

  

0.038

High cervical (C1–C4)

3.542

(1.350, 9.291)

0.010

2.340

(1.037, 5.278)

0.041

Low cervical (C5–T1)

1.366

(0.514, 3.628)

0.531

2.509

(1.215, 5.184)

0.013

Thoracic/thoracolumbar (T2–L2)

–

–

 

–

–

 

Baseline neurological examination time (hours post-injury):

1.636

(0.823, 2.326)

0.845

1.159

(0.859, 2.153)

0.658

Time from injury to surgery

  

0.696

  

0.024

 ≤ 8 h

0.703

(0.185, 2.676)

0.605

0.221

(0.062, 0.795)

0.021

8–24 h

1.255

(0.550, 2.862)

0.589

0.503

(0.224, 1.131)

0.096

 > 24 h

–

–

 

–

–

 

Treated with high-dose methylprednisolone

2.870

(1.314, 6.266)

0.008

2.275

(1.249, 4.143)

0.007

  1. The bold font indicates that the corresponding P value is less than 0.05
  2. ISS Injury Severity Score, AIS American Spinal Injury Association Impairment Scale