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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Exosomal miR-331-3p derived from chemoresistant osteosarcoma cells induces chemoresistance through autophagy

Fig. 1

a The expression of miR-331-3p in osteosarcoma cell lines and the osteoblastic cell line. b Transmission electron microscopy image of exosomes from MG63 and HOS cells (the orange arrow indicates exosomes). c The expression of miR-331-3p and miR-199a in exosomes from non-resistant cells (MG63 and HOS) and CDDP-resistant cells (MG63/CDDP and HOS/CDDP). d Flow cytometry was used to analyze the expression of CD63 and CD81 surface proteins in the supernatant exosomes. e Granulometric analysis of the exosomes. *P < 0.05, **P < 0.01, ***P < 0.001 versus the osteoblastic cell line (NHOst). CDDP, cisplatin

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X