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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Clock gene Per1 regulates rat temporomandibular osteoarthritis through NF-κB pathway: an in vitro and in vivo study

Fig. 3

Down-regulation of Per1 inhibits the expression of Mmp13 and NF-κB pathway induced by IL-1β. A RT-qPCR analysis of Per1 and Mmp13 in chondrocytes of NC, IL-1β, sh-control+IL-1β and sh-Per1+IL-1β groups. B Western blot analysis of PER1, MMP13, P65 and p-P65 in four groups. C The relative protein expression level of PER1, MMP13, P65 and p-P65 in four groups. D The ratio of p-P65/P65 in four groups. Values are displayed as the mean ± SEM. *P < 0.05, **P < 0.01 and ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X