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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Clock gene Per1 regulates rat temporomandibular osteoarthritis through NF-κB pathway: an in vitro and in vivo study

Fig. 2

IL-1β increases the expression of Per1 and Mmp13 and activates the NF-κB pathway in mandibular condylar chondrocytes. A The mRNA levels of Mmp13 and Per1 after stimulation of IL-1β in chondrocytes. B, C Protein level and analysis of MMP13, PER1, P65 and p-P65 after stimulation of IL-1β in chondrocytes. D The ratio of p-P65/P65 in two groups. Values are displayed as the mean ± SEM. *P < 0.05 and **P < 0.01

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X