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Table 3 Factors affecting the healing of diabetic foot ulcers

From: Comparison of customized vacuum sealing drainage and vacuum sealing drainage in the treatment of diabetic foot ulcers: a retrospective analysis

Groups

Non-healing group (n = 23)

Healing group (n = 60)

t/Z/χ2 value

P value

Age (years)

72.91 ± 11.23

64.37 ± 11.13

3.125

0.002

Sex

  

2.688

0.101

 Man

10 (43.5%)

38 (63.3%)

  

 Women

13 (56.5%)

22 (36.7%)

  

Duration of diabetes mellitus, years

  

1.561

0.118

Wagner Grading

  

5.645

 < 0.001

 Level 2

2 (8.7%)

22 (36.7%)

  

 Level 3

3 (13.0)

36 (60.0%)

  

 Level 4

18 (78.3%)

2 (3.3%)

  

Treatment method

  

16.207

 < 0.001

 Customized VSD

4 (17.4%)

40 (66.7%)

  

 VSD

19 (82.6%)

20 (33.3%)

  

FPG (mmol/L)

8.94 (7.26–12.03)

10.0 (7.0–13.4)

0.605

0.545

HbA1c (%)

8.6 (7.2–10.5)

9.10 (7.53–11.05)

0.509

0.611

BMI (kg/m2)

23.0 (21.43–23.80)

22.38 (21.01–24.05)

0.290

0.772

TC (mmol/L)

4.53 ± 1.12

4.05 ± 1.10

1.785

0.078

TG (mmol/L)

1.37 (1.15–1.91)

1.28 (0.91–1.62)

1.201

0.230

HDL-C (mmol/L)

0.96 (0.83–1.28)

0.86 (0.68–1.04)

2.036

0.042

LDL-C (mmol/L)

2.52 ± 0.71

2.40 ± 0.78

0.626

0.533

SBP (mmHg)

138 (125–146)

138 (128–144.75)

0.127

0.899

DBP (mmHg)

75 (70–86)

75 (68.25–80)

1.076

0.282

Hemoglobin (g/L)

119 (108–135)

119.5 (108–133.5)

0.158

0.875

Fasting C-peptide (ug/L)

1.21 (0.83–2.30)

2.31 (1.55–3.28)

3.465

0.001

  1. BMI: body mass index; FPG: fasting plasma glucose; TC: total cholesterol; TG: triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HbA1c: glycated hemoglobin; SBP: systolic blood pressure; DBP: diastolic blood pressure