Fig. 3
From: Adipose-derived stem cell exosome NFIC improves diabetic foot ulcers by regulating miR-204-3p/HIPK2
HIPK2 overexpression might abolish the influences of miR-204-3p on HG-mediated HUVEC behaviors. HUVECs were transfected with miR-NC, miR-204-3p, miR-204-3p + pcDNA, and miR-204-3p + pcDNA-HIPK2, followed by HG treatment. A Western blot analysis of HIPK2 protein level in treated HUVECs. B and C HUVEC proliferative ability was analyzed using CCK-8 and EdU assays. D HUVEC apoptosis rate was examined using flow cytometry assay. E HUVEC migration rate was assessed using wound healing assay. F HUVEC tube formation ability was evaluated using Tube formation assay. *P < 0.05