Table 3 Subgroup analysis of included studies evaluating for causes of presumed variability amongst studies
Sensitivity (95% CI) | Specificity (95% CI) | AUROC (95% CI) | |
|---|---|---|---|
All | 85% (77–90%) | 96% (93–97%) | 0.97 (0.95–0.98) |
Qualitative only | 80% (68–88%) | 96% (90–98%) | 0.95 (0.93–0.97) |
Quantitative only | 91% (85–95%) | 95% (94–97%) | 0.98 (0.96–0.99) |
Femur only | 81% (66–91%) | 95% (91–98%) | 0.96 (0.94–0.98) |
Tibia only | 89% (79–95%) | 96% (89–98%) | 0.97 (0.96–0.99) |
North America/Europe | 87% (77–93%) | 93% (88–95%) | 0.96 (0.94–0.97) |
Asia | 80% (71–87%) | 98% (95–99%) | 0.97 (0.95–0.98) |
Prospective | 82% (74–88%) | 95% (91–98%) | 0.95 (0.92–0.96) |
Retrospective* | 89% (62–97%) | 96% (94–97%) | |
Consensus | 81% (70–88%) | 96% (89–98%) | 0.94 (0.91–0.91) |
No consensus | 88% (77–94%) | 96% (95–97%) | 0.96 (0.94–0.98) |
Mean Age 20–39 | 79% (67–88%) | 96% (88–99%) | 0.93 (0.91–0.95) |
Mean Age 40–59 | 88% (79–93%) | 95% (94–96%) | 0.96 (0.94–0.97) |