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Table 1 Patient and study characteristics of included studies

From: Diagnostic accuracy of dual-energy CT for bone marrow edema in patients with acute knee injury: a systematic review and meta-analysis

Author, published year

Country

No. patients (inclusion interval)

Mean age

(range)

Male/female

No. knees with edema (no. regions)

Study design

Time interval between DECT and MRI

No. readers

Consensus reading

Reader experience (years)

Ai [11]

USA

14 (2009.03–2011.07)

24.6

(18–48)

11/3

NR (36/56 regions)

Retrospective

 < 99 days

2

Yes

MSK radiologists (11 + 19)

Bjorkman [12]

Sweden

48 (2017.10–2018.03)

23

(15–37)

26/22

52 (85/192 regions)

Prospective

 < 7 days

2

Yes

Resident (3) + Radiologist (> 7)

Booz [13]

Germany

57 (2017.01–2018.05)

50

(20–82)

27/30

36 (197/684 regions)

Retrospective

 < 7 days

6

No

Qualitative: 4 residents (3–4) + 2 radiologists (7–10)

Quantitative: medical students (2)

Cao [14]

China

32 (2012.04–2012.08)

39.9

(20–60)

24/8

32 (127/384 regions)

Prospective

 ≤ 6 days

2

Yes

Radiologists (vastly experienced)

Foti [15]

Italy

33 (2019.01–2019.06)

52.2

(31–76)

20/13

25 (85/396 regions)

Prospective

 < 6 days

2

Yes

Radiologists (20 + 16)

Juhng [16]

South Korea

23 (NR)

47.4

(14–72)

11/12

NR (84/378 regions)

Prospective

NR

2

No

Radiologists (5 + 25)

Liang [17]

China

23 (2018.07–2019.06)

47

(21–73)

10/13

24 (121/288 regions)

Prospective

NR

5

No

MSK radiologists (8 + 10 + 4 + 5 + 20)

Pache [18]

Germany

21 (2009.01–2009.05)

35.9

(19–60)

16/5

NR (59/236 regions)

Prospective

 ≤ 5 days

2

No

MSK radiologists (5 + 7)

Wang [19]

China

39 (2018.03–2018.11)

36.3

(13–89)

22/17

NR (43/195 regions)

Prospective

 ≤ 5 days

3

Yes

Radiologists (> 5)

  1. No.—number; DECT—dual-energy computed tomography; MRI—Magnetic resonance imaging; NR—not reported