Table 3 Replicated MR analysis by IVW method after removing confounders-related IVs

Family

IVDD

Family Rikenellaceae id.967

0.069

0.903(0.809–1.008)

Family Ruminococcaceae id.2050

0.005

0.813(0.705–0.939)

Genus

Genus Escherichia Shigella id.3504

0.019

1.163(1.025–1.319)

Genus Eubacterium coprostanoligenes group id.11375

0.001

0.801(0.704–0.912)

Genus Gordonibacter id.821

0.028

0.933(0.877–0.993)

Genus Lachnoclostridium id.11308

0.075

0.885(0.774–1.012)

Genus Marvinbryantia id.2005

0.010

1.176(1.039–1.330)

Genus Oscillospira id.2064

0.058

0.885(0.779–1.004)

Phylum

Phylum Bacteroidetes id.905

0.004

1.218(1.065–1.392)