RNA sequencing and bioinformatics analysis of differentially expressed genes in the peripheral serum of ankylosing spondylitis patients

Table 3 Top ten upregulated and ten downregulated DEGs in AS

Gene name	logFC	Fold change	P value	Regulation
SYNE3	13.70024767	13,310.22803	2.53347E−05	Up
NEK9	13.66669431	13,004.23858	2.90169E−05	Up
PPARG	13.62684124	12,649.92523	3.87972E−05	Up
HAT1	13.15463256	9118.827157	0.000323846	Up
STUB	13.0556646	8514.255069	0.000478438	Up
MCM3AP	12.78714097	7068.267708	0.000980806	Up
KIF20A	12.77003424	6984.950792	0.001209986	Up
FAHD1	12.64685533	6413.318437	0.001424853	Up
RBBP8	12.43477239	5536.553204	0.002137449	Up
MARC1	12.1303543	4483.327884	0.003358303	Up
MIF	− 11.57772609	0.000327158	0.003321108	Down
ASCC3	− 11.5932764	0.00032365	0.003319781	Down
CCDC124	− 11.6024601	0.000321597	0.003347325	Down
PMS2	− 11.6352721	0.000314365	0.003485706	Down
NELFB	− 11.82545438	0.000275539	0.002867456	Down
PAMR1	− 12.07196817	0.000232261	0.002207181	Down
VASN	− 12.48849677	0.000174015	0.001089923	Down
SIK1	− 12.54756591	0.000167035	0.001085811	Down
OGDH	− 12.71646833	0.00014858	0.000627557	Down
HBA1	− 13.92287772	6.43867E-05	3.65243E−06	Down

ISSN: 1749-799X