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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Exosomal miR-214-3p from senescent osteoblasts accelerates endothelial cell senescence

Fig. 4

L1CAM as a potential target of miR-214-3p. A Identify potential target gene L1CAM by TargetScan bio-informatics database (This figure is from the TargetScan website). B Expression of L1CAM mRNA in endothelial cells after transfected with miR-214-3p mimic or inhibitor. C The predicted binding site of L1CAM targeted by miR-214-3p. D The dual-luciferase assay verified the targeted relationship between L1CAM and miR-214-3p (p < 0.05; p < 0.01; p < 0.001)

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