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Table 5 Diagnostic accuracy of Modic changes to pain for individual studies

From: Modic changes as seen on MRI are associated with nonspecific chronic lower back pain and disability

Study

Statistics

MC1 versus MC0

MC2 versus MC0

MC3 versus MC0

Braithwaite [58]

Sensitivity (%)

6.76

18.82

4.17

Specificity (%)

100.00

96.77

100.00

PLR

–

5.84

–

NLR

0.93

0.84

0.96

Thompson [53]

Sensitivity (%)

16.43

11.22

1.84

Specificity (%)

98.11

97.09

99.41

PLR

8.68

3.86

3.09

NLR

0.85

0.91

0.99

O’Neill [52]

Sensitivity (%)

6.79

8.04

 

Specificity (%)

99.09

99.09

 

PLR

7.43

8.80

 

NLR

0.94

0.93

 

Weishaupt [51]

Sensitivity (%)

35.90

26.47

 

Specificity (%)

97.01

98.48

 

PLR

12.03

17.47

 

NLR

0.66

0.75

 

Kokkoken [59]

Sensitivity (%)

24.14

24.14

4.35

Specificity (%)

77.78

79.55

97.22

PLR

1.09

1.18

1.57

NLR

0.98

0.95

0.98

  1. For these diagnostic statistic calculations, Pain is used as the reference test
  2. PLR Positive likelihood ratio, NPL Negative likelihood ratio