Fig. 2

Circ_0005615 depletion curbed cell proliferation, cell cycle progression and glycolysis whereas reinforced apoptosis in MM. MM1.S and NCI-H929 cells were transfected with si-NC and si-circ_0005615, individually. A The abundance of circ_0005615 was estimated by using qRT-PCR. B Cell viability was evaluated using CCK-8 assay. C–F Cell proliferation, apoptosis and cell cycle was examined via utilizing EdU assay and flow cytometry. G–H Western blot assay was employed to explore the protein levels of Bax and Bcl-2. I–K Cell glycolysis was analyzed by detecting glucose consumption, lactate production and ATP/ADP ratio through the matched kits. **P < 0.01, ***P < 0.001, ****P < 0.0001