Fig. 6
From: MiR-217 regulates autophagy through OPG/RANKL/RANK in giant cell tumors
Protein expression in the OPG/RANKL/RANK signaling pathway by miR-217 in vivo. a Immunohistochemical staining of the OPG/RANKL/RANK signaling pathway-related protein expression in the tumor tissues (scale bar = 100 μm). b RT-PCR showing changes in the expression of proteins in tumors following transfection with miR-217 mimics or miR-217 inhibitor. c The level of protein (Beclin-1, molecular weight: 60 kDa; LC3-I, molecular weight: 16 kDa; LC3-II, molecular weight: 14 kDa; OPG, molecular weight: 46 kDa; RANK, molecular weight: 55 kDa; and RANKL, molecular weight: 35–45 kDa) expression was detected in the tumors by Western blot. **P < 0.01 versus control