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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: LncRNA ZFAS1 protects chondrocytes from IL-1β-induced apoptosis and extracellular matrix degradation via regulating miR-7-5p/FLRT2 axis

Fig. 6

FLRT2 was a target of miR-7-5p. A Three mRNAs including SSX2IP, FLRT2, and NREP were screened out by performing interaction analysis. B Dual-luciferase reported assay was applied to verify the targeting relationship between miR-7-5p and FLRT2. **P < 0.01, compared with the miR-NC group. C–D FLRT2 mRNA C and protein D expressions were significantly decreased in IL-1β-treated chondrocytes. **P < 0.01, compared with the control group. E–F FLRT2 mRNA and protein expressions were significantly decreased following the transfection with miR-7-5p mimics. **P < 0.01, compared with the miR-NC group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X