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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Metabolomics analysis of the potential mechanism of Yi-Guan-Jian decoction to reverse bone loss in glucocorticoid-induced osteoporosis

Fig. 4

Screening to identify significant markers of YGJ reversal of metabolism in GIOP mice. A Volcano plot analysis of DEX group versus Control and DEX + YGJ groups in positive and negative ion mode; B summary of metabolites of significant differences between DEX group and Control group and DEX + YGJ group in positive and negative ion mode (+ : positive ion mode, − : negative ion mode); C Venn diagram of significant markers of YGJ balance in positive and negative ion mode (↑: up-regulation, ↓: down-regulation); D cluster heat map analysis of 52 significant markers among the three groups

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