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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Metabolomics analysis of the potential mechanism of Yi-Guan-Jian decoction to reverse bone loss in glucocorticoid-induced osteoporosis

Fig. 2

Analysis of bone morphology and serum biochemical markers in GIOP mice. A Micro-CT preaxial, level, and 3D scan views; B quantitative study of Micro-CT bone parameters, including BMD: bone density, BMC: bone mineral content, Tb.Sp: bone trabecular separation (the average width of medullary cavity between bone trabecular), Tb.N: bone trabecular number, SMI: structural pattern index (describing the ratio of lamellar and rod-shaped structure in trabecular structure, If the structure is mainly lamellar structure, SMI is close to 0; otherwise, it is a rod-shaped trabecular structure. It was close to 3), Conn.D: bone trabecular connection density (indicating the number of connections between bone trabecular reticular structures per cubic millimeter volume), BV/TV: bone volume fraction (ratio of bone tissue volume to tissue volume in the selected area), BS/TV: bone surface area tissue volume ratio (bone surface area density); C HE-stained section of the right femur of mice; D average positive optical density value; E effects of YGJ on ALP, OCN and CTX-I levels in GIOP mice.*P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X