The role of SPECT/CT in painful, noninfected knees after knee arthroplasty: a systematic review and meta-analysis—a diagnostic test accuracy review

Table 2 Meta-regression and categorical covariates analysis for sensitivity and specificity of SPECT/CT for diagnosis of painful aseptic loosening knee prosthesis

Covariate	Parameter	Subgroup	Estimate+
Risk of bias	Sen	Some concerns	0.84 (0.56–0.96)*
	Sen	low	0.87 (0.74–0.93)*
	Esp	Some concerns	0.91 (0.69–0.98)*
	Esp	Low	0.90 (0.75–0.97)*
Intraarticular/intravenous radiotracer use	Sens	i.v	0.89 (0.79–0.95)*
	Sens	i.a	0.71 (0.40–0.90)
	Esp	i.v	0.92(0.80–0.97)*
	Esp	i.a	0.88 (0.68–0.97)*
Type	Sen	General	0.86 (0.68–0.95)*
		Femoral	0.73 (0.50–0.88)
		Tibial	0.87 (0.68–0.95)*
		Patellar	0.98 (0.85–1.00)*
	Esp	General	0.92 (0.74–0.98)*
		Femoral	0.80 (0.39–0.96)
		Tibial	0.90 (0.56–0.98)*
		Patellar	0.94 (0.41–1.00)

ISSN: 1749-799X