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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Anemonin reduces hydrogen peroxide-induced oxidative stress, inflammation and extracellular matrix degradation in nucleus pulposus cells by regulating NOX4/NF-κB signaling pathway

Fig. 6

ANE suppressed H2O2-induced degeneration of extracellular matrix in NPCs through inactivating NOX4/NF-κB pathway. A–F The expression of MMP-3, MMP-13, ADAMTS-4, ADAMTS-5 and collagen II was measured by western blot. G–I Western blot showing the expression of NOX4, NF-κB and p- NF-κB. **p < 0.01 versus control group. ##p < 0.01 versus H2O2 treatment group. &&p < 0.01 versus ANE + H2O2 treatment group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X