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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Sexual dimorphism in reactive oxygen species production and a role for integrin α1β1 in estrogen receptor α and β expression in articular cartilage

Fig. 3

Confocal microscopy images of tibial and femoral cryosections showing the articular cartilage from the lateral compartment of itga1-null and wild-type male mice immunostained green for pEGFR (A). Secondary antibody only control sections show negligible autofluorescence from the murine cartilage. Nuclei were counterstained blue with Hoechst as seen in the differential interference contrast (DIC) images. Scale bar 50 μm. Percent of chondrocytes stained positively for pEGFR as a function of genotype and site (B) or sex (C). Data points are means (N = 6 femora, n > 800 cells) ± 95% CI. Genotype effect dashed bracket and site effect solid bracket, p < 0.001 (a), p = 0.014 (b)

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X