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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Piperine improves the sensitivity of osteosarcoma cells to doxorubicin by inducing apoptosis and inhibiting the PI3K/AKT/GSK-3β pathway

Fig. 2

Effect of PIP combined with DOX on scratch healing in osteosarcoma cells. Cells were scratched using a 100 μL tip and then treated with PBS, PIP, DOX, and PIP + DOX. Scratch healing was observed at 0, 12 and 24 h after scratching. A Wound healing area of U2OS and 143B cells in each treatment group. B Quantification of migration rates. *P < 0.05, **P < 0.01, ***P < 0.001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X