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Fig. 6 | Journal of Orthopaedic Surgery and Research

Fig. 6

From: Functional heterogeneity of MCT1 and MCT4 in metabolic reprogramming affects osteosarcoma growth and metastasis

Fig. 6

Effects of MCT1 and/or MCT4 inhibition on protein expression and localization of p65 and c-Myc in MNNG/HOS cells. A Representative immunofluorescence pictures and relative fluorescent intensity of p65 with treatment of DMSO, 10 µM AZD3965 (AZD), 10 µM VB124 (VB) and AZD + VB. B Representative immunofluorescence pictures and relative fluorescent intensity of c-Myc in cells treated with DMSO, AZD3965, VB124 and AZD + VB. C Protein expressions of p65 and c-Myc in cells treated with DMSO, AZD3965, VB124 and AZD + VB. Data are shown as mean ± standard deviation (SD). Statistical differences are obtained by comparison with DMSO group. *p < 0.05, **p < 0.01, ***p < 0.001; ns, not significant

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X