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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: DEPDC1 and KIF4A synergistically inhibit the malignant biological behavior of osteosarcoma cells through Hippo signaling pathway

Fig. 1

DEPDC1 was highly expressed in OS cells, and down-regulation of DEPDC1 inhibited cell proliferation. A/B The expression of DEPDC1 in OS cells was detected by RT-qPCR and western blot. ***P < 0.001 versus hFOB1.19 group. C/D The transfection effects of sh-DEPDC1#1 and sh-DEPDC1#2 in U2OS cells was confirmed by RT-qPCR and western blot. E The viability of U2OS cells transfected with si-DEPDC1 was determined by CCK-8 assay. F The proliferation of U2OS cells transfected with sh-DEPDC1 was observed by EdU staining. G The expression of PCNA in U2OS cells transfected with sh-DEPDC1 was detected by western blot. ***P < 0.001 versus Control group. ###P < 0.001 versus sh-NC group. +P < 0.05 versus sh-DEPDC1#1

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X