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Fig. 9 | Journal of Orthopaedic Surgery and Research

Fig. 9

From: Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathway

Fig. 9

Nesfatin-1 significantly precluded OA exacerbation in vivo via inhibiting the activation of RhoA/ROCK pathway. Immunohistochemical staining of the downstream proteins of RhoA/ROCK pathway including Cofilin-2, p-Cofilin-2, LIMK1 and p-LIMK1 in different groups. ***p < 0.001 compared with OA group; nsd means no significant difference

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