Fig. 9From: Nesfatin-1 suppresses autophagy of chondrocytes in osteoarthritis via remodeling of cytoskeleton and inhibiting RhoA/ROCK signal pathwayNesfatin-1 significantly precluded OA exacerbation in vivo via inhibiting the activation of RhoA/ROCK pathway. Immunohistochemical staining of the downstream proteins of RhoA/ROCK pathway including Cofilin-2, p-Cofilin-2, LIMK1 and p-LIMK1 in different groups. ***p < 0.001 compared with OA group; nsd means no significant differenceBack to article page