Table 2 Association between total cholesterol (mmol/L) and total bone mineral density (g/cm2)
Model 1, β (95%, CI) | Model 2, β (95%, CI) | Model 3, β (95%, CI) | |
|---|---|---|---|
P value | P value | P value | |
Serum cholesterol (mmol/L) | − 0.0070 (− 0.0090, − 0.0051) | − 0.0038 (− 0.0058, − 0.0019) | − 0.0036 (− 0.0057, − 0.0015) |
< 0.001 | < 0.001 | < 0.001 | |
Quintiles of cholesterol | |||
Lowest quintiles (0.15–4.23 mmol/L) | Reference | Reference | Reference |
Q2(1.50–4.20 mmol/L) | − 0.0072 (− 0.0131, − 0.0013) | 0.0005 (− 0.0050, 0.0059) | − 0.0001 (− 0.0055, 0.0053) |
Q3(4.81–5.51 mmol/L) | − 0.0114 (− 0.0173, − 0.0055) | − 0.0025 (− 0.0080, 0.0030) | − 0.0040 (− 0.0095, 0.0015) |
Q4(5.52–21.02 mmol/L) | − 0.0201 (− 0.0259, − 0.0142) | − 0.0112 (− 0.0169, − 0.0056) | − 0.0109 (− 0.0168, − 0.0050) |
P for trend | < 0.001 | < 0.001 | < 0.001 |
Stratified by gender | |||
Men | − 0.0053 (− 0.0081, -0.0025) | − 0.0030 (− 0.0058, − 0.0002) | − 0.0037 (− 0.0067, − 0.0006) |
< 0.001 | 0.0198 | 0.020 | |
Women | − 0.0086 (− 0.0112, − 0.0061) | − 0.0041 (− 0.0068, − 0.0015) | − 0.0037 (− 0.0065, − 0.0008) |
< 0.001 | 0.002 | 0.011 | |
Stratified by race/ethnicity | |||
Non-Hispanic White | − 0.0065 (− 0.0098, − 0.0032) | − 0.0044 (− 0.0076, − 0.0011) | − 0.0040 (− 0.0075, − 0.0004) |
< 0.001 | 0.009 | 0.028 | |
Non-Hispanic Black | − 0.0061 (− 0.0111, − 0.0012) | − 0.0012 (− 0.0060, 0.0037) | − 0.0005 (− 0.0056, 0.0046) |
0.014 | 0.632 | 0.844 | |
Mexican American | − 0.0014 (− 0.0062, 0.0035) | − 0.0024 (− 0.0072, 0.0024) | − 0.0028 (− 0.0081, 0.0026) |
0.584 | 0.329 | 0.316 | |
Other race/ethnicity | − 0.0064 (− 0.0100, − 0.0028) | − 0.0045 (− 0.0080, − 0.0010) | − 0.0047 (− 0.0086, − 0.0008) |
< 0.001 | 0.0126 | 0.017 | |
Stratified by age | |||
20 ≤ Age < 30 | − 0.0033 (− 0.0079, 0.0012) | − 0.0017 (− 0.0059, 0.0025) | − 0.0040 (− 0.0086, 0.0006) |
0.152 | 0.437 | 0.086 | |
30 ≤ Age < 40 | − 0.0012 (− 0.0054, 0.0030) | − 0.0046 (− 0.0086, − 0.0007) | − 0.0030 (− 0.0073, 0.0013) |
0.575 | 0.020 | 0.168 | |
40 ≤ Age < 50 | − 0.0008 (− 0.0045, 0.0030) | − 0.0008 (− 0.0043, 0.0027) | − 0.0006 (− 0.0045, 0.0033) |
0.689 | 0.6617 | 0.770 | |
50 ≤ Age < 60 | − 0.0166 (− 0.0208, − 0.0124) | − 0.0049 (− 0.0068, − 0.0030) | − 0.0048 (− 0.0069, − 0.0028) |
< 0.001 | < 0.001 | < 0.001 | |