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Table 3 Results of bone histomorphometry for control and diabetic rats

From: Histological assessment of cortical bone changes in diabetic rats

 

Control

Diabetic

p-value

Ct.Ar (mm2)

5.2 ± 0.3

4.3 ± 0.2

 < 0.001

Ma.Ar (mm2)

1.5 ± 0.2

1.0 ± 0.1

 < 0.001

Ma.Ar/Ct.Ar (%)

23.2 (17.7–25.0)

18.5 (18.0–20.4)

0.01

OS (%)

28.5 (0.0–75.3)

15.7 (0.0–30.1)

0.28

ES (%)

5.9 (3.3–11.7)

6.5 (4.0–15.3)

0.44

MS/BS (Ps) (%)

9.6 (0.0–46.8)

10.0 (0.0–23.9)

0.88

MS/BS (Es) (%)

1.0 (0.0–7.3)

0.0 (0.0–8.2)

0.33

MS/BS (Ps + Es) (%)

6.8 (0.0–31.2)

7.2 (0.0–19.2)

0.65

MAR (µm/day)

0.4 ± 0.4

0.5 ± 0.4

0.72

BFR/BS (µm3/µm2/day)

0.12 ± 0.15

0.08 ± 0.07

1.00

Ct.P (%)

0.7 (0.6–0.9)

0.6 (0.4–0.6)

 < 0.001

N.Ot/BV

776 (523–1083)

601 (518–870)

0.03

  1. Values are expressed as means ± standard deviations for parametric parameters and as medians and ranges for nonparametric parameters
  2. Ct.Ar cortical area, Ma.Ar marrow area, OS osteoid surface in periosteum, ES eroded surface in periosteum, MS mineralizing surface, BS bone surface, PS periosteal, ES endosteal, MAR mineral apposition rate, BFR bone formation rate, Ct.P cortical porosity, N.Ot osteocyte number, BV bone volume