Fig. 6

Ginsenoside Rg1 inhibits the inflammatory response, oxidative stress and extracellular matrix degradation of nucleus pulposus cells in rats with intervertebral disc degeneration. A–D: Levels of TNF-α, IL-6, IL-1β, and PGE2 in the supernatant of NP cells in each group; E–F: Activities of ROS and MDA in the supernatant of NP cells in each group; G–J: mRNA levels of ECM-related genes MMP13, ADAMTS-5, COL II, and ACAN. *p < 0.05 versus Normal group; ^#p < 0.05 versus IDD group