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Table 2 Univariate analysis of variables between infection and non-infection group after PSM

From: Risk factors for deep surgical site infection following surgically treated peri-ankle fractures: a case–control study based on propensity score matching

Variable

Infection group (n = 70)

Non-infection group (n = 140)

P

Obesity

16 (22.9)

18 (12.9)

0.064

Dislocation

7 (10.0)

15 (10.7)

0.873

Hypertension

15 (10.7)

11 (15.7)

0.300

Diabetes

24 (17.1)

11 (15.7)

0.793

Cerebrovascular disease

9 (6.4)

5 (7.1)

0.845

Heart disease

5 (3.6)

3 (4.3)

0.799

Liver disease

2 (1.4)

2 (2.9)

0.475

Renal disease

0

1 (1.4)

0.156

History of any surgery

22 (31.4)

22 (15.7)

0.008

Interval from injury to operation (days)

7.3 ± 5.4

5.9 ± 3.1

0.016

 4–10

33 (47.1)

105 (75.0)

< 0.001

 < 4

12 (17.1)

10 (7.1)

 

 > 10

25 (35.7)

25 (17.9)

 

Surgical wound classification

   

 Type I (clean)

62 (74.3)

132 (94.3)

< 0.001

 Type II (clean–contaminated)

18 (25.7)

8 (5.7)

 

Anesthesia pattern

  

0.110

 Regional

52 (74.3)

117 (83.6)

 

 General

18 (25.7)

23 (16.4)

 

Injury mechanism

  

0.076

 Low to medium energy

13 (18.6)

42 (30.0)

 

 High energy

57 (81.4)

98 (70.0)

 

Fracture type based on AO classification system

  

0.990

 44A

21 (30.0)

39 (28.1)

 

 44B

10 (14.3)

25 (18.0)

 

 44C

7 (10.0)

12 (8.6)

 

 81A

1 (1.4)

1 (0.7)

 

 81B

2 (2.9)

4 (2.9)

 

 81C

2 (2.9)

5 (3.6)

 

 82B

10 (14.3)

16 (11.5)

 

 82C

17 (24.3)

37 (26.6)

 

Current smoking

21 (30.0)

23 (16.4)

0.023

Alcohol drinking

39 (55.7)

57 (40.7)

0.040

Reduction method

  

0.868

 Closed

7 (10.0)

13 (9.3)

 

 Open

63 (90.0)

127 (90.7)

 

Internal fixation hardware

  

0.579

 Plate/screw

55 (78.6)

104 (74.3)

 

 Screw only

11 (15.7)

30 (21.4)

 

 Others

4 (5.7)

6 (4.3)

 

Bone grafting

  

0.474

 Yes

7 (10.0)

10 (7.1)

 

 No

63 (90.0)

130 (92.9)

 

Surgical duration (minutes)

143.4 ± 64.0

137.1 ± 62.1

0.495

 ≥ 180 min

21 (30.0)

29 (20.7)

0.136

Intraoperative blood loss (ml)

214.4 ± 272.0

178.4 ± 261.5

0.354

 ≥ 300 ml

17 (24.3)

23 (16.4)

0.172

ASA classification

  

0.315

 I

11 (15.7)

27 (19.3)

 

 II

49 (70.0)

102 (72.9)

 

 III–IV

10 (14.3)

11 (7.9)

 

Allogeneic transfusion

2 (1.4)

4 (5.7)

0.079

BMI (kg/m2)

26.1 ± 4.1

25.8 ± 3.8

0.639

 Obesity (BMI ≥ 30)

16 (22.9)

18 (12.9)

0.064

Albumin (g/L)

39.6 ± 7.5

40.9 ± 4.8

0.141

 < 35

13 (18.6)

14 (10.0)

0.080

FBG (mmol/L)

5.9 ± 2.1

5.8 ± 1.4

0.620

 ≥ 6.1

16 (22.9)

39 (27.9)

0.437

RBC (*1012/L)

4.1 ± 0.7

4.3 ± 0.6

0.047

 < Lower limit

25 (35.7)

31 (22.1)

0.036

Hemoglobin (g/L)

124.5 ± 22.6

133.6 ± 18.5

0.002

 < Lower limit

23 (32.9)

20 (14.3)

0.002

Hematocrit (%)

36.8 ± 6.5

39.5 ± 5.3

0.002

 < Lower limit

44 (62.9)

61 (43.6)

0.008

Platelet count (*109/L)

251.2 ± 117.3

238.3 ± 76.4

0.344

 > 300

14 (20.0)

21 (15.0)

0.359

Plateletcrit (%)

0.21 ± 0.11

0.19 ± 0.06

0.168

 < 0.16

18 (25.7)

29 (20.7)

0.413

WBC count (*109/L)

9.0 ± 2.6

8.9 ± 3.0

0.795

 > 10

23 (32.9)

43 (30.7)

0.753

Neutrophil count (*109/L)

6.4 ± 2.3

6.5 ± 2.9

0.975

 > 6.3

23 (41.4)

64 (45.7)

0.556

Lymphocyte count (*109/L)

1.6 ± 0.6

1.6 ± 0.8

0.658

 < 1.1

15 (21.4)

28 (20.0)

0.809

  1. Bold indicates Infection group: patients with an SSI; Non-infection group: patients without an SSI
  2. BMI, body mass index; WBC, white blood cell count; FBG, fasting blood glucose; ASA, American Society of Anesthesiologists RBC, red blood cells, reference range: male, 4.0–5.5 × 1012/L, female, 3.5–5.0 × 1012/L. Hemoglobin, male, ≥ 120 g/L, female, ≥ 110 g/L; hematocrit, reference range: male, 40–50%; female, 35–45%