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Table 2 Subgroup analysis of the effect of different devices on cervical alignment

From: Changes in cervical alignment of Zero-profile device versus conventional cage-plate construct after anterior cervical discectomy and fusion: a meta-analysis

 

Subgroup title

No. of studies

No. of participants (ZP)

No. of participants (CP)

Subgroup outcome

Test for subgroup differences: I2 (%)

Subtotal (95%CI)

P

I2 (%)

Cobb (preoperative)

No. of levels

       
 

 1

5

214

258

− 0.36 [− 1.08, 0.36]

0.32

0

0

 

 ≥ 2

8

299

327

− 0.23 [− 0.78, 0.33]

0.43

0

 

Cobb (postoperative)

No. of levels

       
 

 1

5

214

258

− 0.72 [− 2.24, 0.81]

0.36

76

0

 

 ≥ 2

8

299

327

− 0.91 [− 1.76, − 0.07]

0.03*

38

 

Cobb (last follow-up)

No. of levels

       
 

 1

4

197

234

− 1.70 [− 2.42, − 0.99]

< 0.00001*

23

67.9

 

 ≥ 2

7

233

243

− 0.83 [− 1.48, − 0.18]

0.01*

49

 
 

Years of the last follow-up

       
 

 < 3

7

265

265

− 1.07 [− 2.21, 0.06]

0.06

46

0

 

 ≥ 3

4

165

212

− 1.62 [− 2.56, − 0.67]

0.0008*

36

 

IDH (preoperative)

No. of levels

       
 

 1

2

101

146

0.03 [− 0.25, 0.30]

0.83

0

0

 

 ≥ 2

5

163

173

0.02 [− 0.06, 0.11]

0.6

0

 

IDH (postoperative)

No. of levels

       
 

 1

2

101

146

− 0.00 [− 0.20, 0.20]

0.98

0

0

 

 ≥ 2

5

163

173

0.10 [− 0.02, 0.22]

0.11

34

 

IDH (last follow-up)

No. of levels

       
 

 1

2

101

146

− 0.09 [− 0.29, 0.12]

0.42

0

0

 

 ≥ 2

5

163

173

− 0.02 [− 0.31, 0.27]

0.89

76

 
 

Years of the last follow-up

       
 

 < 3

4

136

139

0.09 [− 0.17, 0.36]

0.49

55

60.1

 

 ≥ 3

3

128

180

− 0.18 [− 0.40, 0.03]

0.1

39

 

ASD

No. of levels

       
 

 1

3

170

218

0.54 [0.33, 0.88]

0.01*

0

0

 

 ≥ 2

7

286

311

0.37 [0.20, 0.70]

0.002*

0

 
 

Years of the last follow-up

       
 

 < 3

6

258

275

0.39 [0.18, 0.83]

0.01*

0

0

 

 ≥ 3

4

198

254

0.41 [0.23, 0.70]

0.001*

0

 

Dysphagia (postoperative)

No. of levels

       
 

 1

2

62

63

0.68 [0.27, 1.71]

0.41

0

0

 

 ≥ 2

3

97

104

0.74 [0.41, 1.34]

0.32

0

 

Dysphagia (2 or 3 months)

No. of levels

       
 

 1

3

84

88

0.21 [0.06, 0.80]

0.02*

0

0

 

 ≥ 2

5

147

160

0.15 [0.07, 0.33]

< 0.00001*

0

 

Dysphagia (6 months)

No. of levels

       
 

 1

2

57

58

0.13 [0.02, 1.07]

0.06

0

0

 

 ≥ 2

4

149

156

0.10 [0.03, 0.37]

0.0006*

0

 

Dysphagia (last follow-up)

No. of levels

       
 

 1

1

27

30

0.36 [0.01, 9.15]

0.53

–

0

 

 ≥ 2

4

118

125

0.48 [0.20, 1.15]

0.1

0

 
  1. *Statistically significant