Fig. 1

A typical case. A A 26-year-old female who suffered from comminuted femoral fracture in the distal section, two anatomical plates were used in the preliminary surgery, osteomyelitis occurred 3 months later with a sinus tract formation at inner side of thigh; B CT scan shows infective osteonecrosis in the distal section of left femur; C Removed the internal fixation and necrosis bone, the length of infective bone was approximate 15.9 cm; D Antibiotics-loaded bone cement spacer implanted into the defect section after debridement, combined with temporary fixation by a locking titanium plate on the lateral side of femur; E the photograph of real product, the prominent structure could insert into the medullary cavity to increase the contact area between the bone and prosthesis. F In the stage 2, remove all implantation in stage 1 and protected the self-induced membrane; G filled the segmental bone defect area with the scaffolds; H 13 months later, radiological tests showed satisfactory osseointegration of the scaffolds and stability fixation