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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Circ_0083964 knockdown impedes rheumatoid arthritis progression via the miR-204-5p-dependent regulation of YY1

Fig. 5

YY1 was a direct target of miR-204-5p. A StarBase dataset was used to predict the binding region between YY1 and miR-204-5p. B, C The target interaction between miR-204-5p and YY1 was tested by dual-luciferase reporter assay and RIP assay. D The mRNA level of YY1 was obtained in RA synovial tissues by qRT-PCR. E The linear relationship between the expression of YY1 and miR-204-5p was examined by Pearson correlation analysis. F, G Western blot assay was applied to illustrate the protein expression of YY1 in RA synovial tissues and RA-FLSs. ***P < 0.001, ****P < 0.0001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X