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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Circ_0083964 knockdown impedes rheumatoid arthritis progression via the miR-204-5p-dependent regulation of YY1

Fig. 3

MiR-204-5p was a direct target of circ_0083964 in RA-FLSs. A StarBase and circBank databases showed three miRNAs that were targeted by circ_0083964. B The effect of circ_0083964 knockdown on the expression of three miRNAs was examined by qRT-PCR. C The binding regions with miR-204-5p in circ_0083964 were shown. D, E Dual-luciferase reporter assay and RIP assay were applied to analyze the target interaction between circ_0083964 and miR-204-5p. F The expression of miR-204-5p was examined in RA synovial tissues and normal tissues by qRT-PCR. G The correlation between the level of circ_0083964 and miR-204-5p was explored by Pearson correlation analysis. H The miR-204-5p level was estimated by qRT-PCR in RA-FLSs and control cells. **P < 0.01, ***P < 0.001, ****P < 0.0001

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X