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Table 4 Patients’ functional outcome pre- and 1-year postoperatively in terms of genotypes (mean ± SD)

From: Anterior cruciate ligament injury and its postoperative outcomes are not associated with polymorphism in COL1A1 rs1107946 (G/T): a case–control study in the Middle East elite athletes

Outcome

Preoperative

1-year postoperative

P value

GG (n = 124)

GT (n = 43)

TT (n = 33)

GG (n = 120)

GT (n = 40)

TT (n = 30)

Anterior knee pain (VAS)

5.0 ± 1.4

5.0 ± 1.6

4.9 ± 1.5

2.3 ± 1.1

2.6 ± 1.1

2.6 ± 1.1

Group effect: 0.80

Time effect: < 0.001

Interaction: 0.43

Drawer test (mm)

6.1 ± 1.2

6.3 ± 1.3

5.8 ± 1.4

1.5 ± 0.5

1.7 ± 0.7

1.5 ± 0. 6

Group effect: 0.09

Time effect: < 0.001

Interaction: 0.31

Lachman test (mm)

6.5 ± 1.2

6.3 ± 1.2

6.3 ± 1.2

1.5 ± 0.5

1.7 ± 0.6

1.6 ± 0.6

Group effect: 0.81

Time effect: < 0.001

Interaction: 0.16

IKDC knee score

63.5 ± 6.0

65.0 ± 8.0

61.4 ± 10.4

86.2 ± 4.1

86.1 ± 4.4

85.9 ± 3.5

Group effect: 0.27

Time effect: < 0.001

Interaction: 0.07

KOOS

61.7 ± 4.7

61.5 ± 4.9

60.3 ± 5.5

86.2 ± 4.1

86.1 ± 4.4

85.9 ± 3.5

Group effect: 0.50

Time effect: < 0.001

Interaction: 0.69

Tegner Lysholm

65.7 ± 4.4

65.0 ± 3.7

66.1 ± 4.2

88.4 ± 3.0

88.7 ± 2.6

89.0 ± 2.8

Group effect: 0.19

Time effect: < 0.001

Interaction: 0.53

ACL-RSI

29.1 ± 8.4

29.4 ± 7.8

27.8 ± 6.0

88.5 ± 7.8

88.9 ± 8.1

91.6 ± 8.8

Group effect: 0.73

Time effect: < 0.001

Interaction: 0.12

  1. *Two-way repeated measure ANOVA
  2. VAS visual analog scale, IKDC international knee documentation committee, KOOS knee injury and osteoarthritis outcome score, ACL-RSI ACL-Return to Sport after Injury, G Guanine, T Thymine