Journal of Orthopaedic Surgery and Research

Table 3 Clinical outcomes of the included studies

From: Platelet-rich plasma use in meniscus repair treatment: a systematic review and meta-analysis of clinical studies

Clinical outcomes		Yang et al. [26]	Bailey et al. [25]	Kaminski et al. [34]	Everhart et al. [33]	Dai et al. [19]	Kemmochi et al. [32]	Kaminski et al. [31]	Pujol et al. [30]	Griffin et al. [20]
IKDC score	PRP	75.1 ± 13.6	87.6 ± 13.3				87.4 ± 10.4	97.56 ± 0.63	90.7	69 ± 26
	Control	72.6 ± 15.8	88.1 ± 12.6				91.5 ± 1.2	84.77 ± 0.92	87.9	76 ± 17
	P value	0.593	0.952				0.13	0.001		0.288
Lysholm knee scale	PRP	80.6 ± 14.9				79.8 ± 9.6	95.8 ± 7.1			66 ± 31.9
	Control	77.7 ± 17.2				74.6 ± 11.6	97.2 ± 1.8			89 ± 9.7
	P value	0.670				0.306	0.69			0.065
VAS score	PRP			1.97 ± 0.05		1.2 ± 1.0		0.84 ± 0.10
	Control			2.05 ± 0.08		1.6 ± 1.1		0.89 ± 0.08
	P value			0.39		0.321		0.15
SANE score	PRP		91.6 ± 11.2
	Control		92.4 ± 10.6
	P value		0.599
WOMAC score	PRP			9.72 ± 0.32				0.95 ± 0.13
	Control			7.50 ± 0.59				3.95 ± 0.33
	P value			0.21				0.002
Tegner activity level score	PRP						5.9 ± 2.3
	Control						7.8 ± 1.6
	P value						0.11
Failure rate	PRP	6.7%		48.0%	14.6%	7.1%		15%	5.8%	26.7%
	Control	12.9%		70.0%	17.0%	13.3%		53%	11.8%	25.0%
	P value	0.874		0.04	0.60	0.58		0.048	0.54	0.89
KOOS
(i) Pain	PRP			87.24 ± 0.36				96.06 ± 0.23	93.3
	Control			89.00 ± 0.63				92.85 ± 0.43	78.4
	P value			0.22				0.035	0.046
(ii) Symptoms	PRP			92.03 ± 0.27				96.23 ± 0.31	90.9
	Control			90.42 ± 0.56				92.33 ± 0.48	86.1
	P value			0.27				0.029
(iii) ADL	PRP			89.36 ± 0.36				98.18 ± 0.13	97.2
	Control			92.38 ± 0.61				95.14 ± 0.38	93.8
	P value			0.25				0.0004
(iv) Sport/recreation	PRP			69.52 ± 0.77				89.44 ± 0.86	88.8
	Control			78.98 ± 1.10				77.56 ± 1.26	74.4
	P value			0.11				0.009	0.03
(v) QoL	PRP			67.06 ± 0.55				80.90 ± 1.09	78.3
	Control			68.18 ± 1.08				66.18 ± 1.17	74.6
	P value			0.42				0.008

PRP Platelet-rich plasma; VAS Visual analog scale; IKDC International knee documentation committee; WOMAC Western Ontario and McMaster universities Osteoarthritis index; KOOS Knee injury and osteoarthritis outcome score; SANE Single assessment numeric evaluation; ADL Activities of daily living; QOL quality of life. P value: Differences in continuous variables were assessed by two-tailed Mann–Whitney U test or unpaired t test and a chi-square test was used for categorical variables. A Kaplan–Meier survival plot was created for meniscal repair failure rate

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