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Table 1 Bone radiographic findings of rat femur and radiographic statistical analysis

From: The effects of romosozumab combined with active vitamin D3 on fracture healing in ovariectomized rats

 

Sham

C

R

VD

R + VD

 

Four-point scale (point)

0.75 ± 1.5

0.7 ± 0.8

0.4 ± 0.5

1.3 ± 1.9

2.3 ± 1.6

RUST (point)

8.4 ± 1.4

8.0 ± 1.0

7.4 ± 1.3

6.7 ± 1.3

7.9 ± 0.9

  1. Sham, sham group; C, control group; R, romosozumab group; VD, active vitamin D3 group; and R + VD, romosozumab + active vitamin D3 group. The fracture line was clear in the C group. In contrast, fracture lines were unclear in the R group, VD group, and R + VD group, whereas abundant callus formation was observed for the R and R + VD groups. No significant differences were observed in the four-point test and RUST scores between the groups