Fig. 1
Study schema. Control group (C: administered saline), romosozumab group (R: subcutaneous romosozumab injection 25 mg/kg/once a month), vitamin D3 group (VD: subcutaneous vitamin D3 injection 0.2 µg/kg/twice a week), R + VD group. Following ovariectomy, 40 female Sprague–Dawley rats (aged 24 weeks) were divided into four groups (n = 10 in each group). After 8 weeks, femoral osteotomy was performed. At 18 weeks, rats were killed, and femoral bone and blood samples were taken