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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: Circular RNA circ_0008365 regulates SOX9 by targeting miR-338-3p to inhibit IL-1β-induced chondrocyte apoptosis and extracellular matrix degradation

Fig. 7

Circ_0008365 was secreted by exosomes in the serum of OA patients. A Exosomes (indicated by red arrows) derived from serum of OA patients and normal people were detected by electron microscope; B The protein levels of CD63 and TSG101 were measured by western blot assay; C The relative expression of circ_0008365 was measured by qRT-PCR in exosome derived from serum of OA patients (n = 25) and healthy controls (n = 20); D The receiver operating characteristic (ROC) curve analysis for exosomal circ_0008365 in diagnosing OA. ***P < 0.001

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