Skip to main content
Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Metformin alleviates osteoarthritis in mice by inhibiting chondrocyte ferroptosis and improving subchondral osteosclerosis and angiogenesis

Fig. 5

Metformin attenuates Erastin-induced ferroptosis in mouse chondrocytes. Immunohistochemical staining of A GPX4, B SLC7A11, C p53 and D ACSL4 (scale bar, 100 µm). Arrows indicate positive cells and E GPX4, F SLC7A11, G P53 and H ACSL4-positive cell proportions. One-way ANOVA and Tukey’s multiple comparison tests were used to compare the data. ***P < 0.001

Back to article page

Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X