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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: HDAC1 regulates inflammation and osteogenic differentiation of ankylosing spondylitis fibroblasts through the Wnt-Smad signaling pathway

Fig. 2

Proteins expression of HDAC1 in AS fibroblasts after different treatment. A The expression of HDAC1 was overexpressed by AAV-HDAC1, and the protein expression was detected by western blot analysis. B Densitometry analysis of protein expression. C Gene expression of HDAC1 in AS fibroblasts after AAV-HDAC1 treatment was detected by RT-PCR analysis. D Protein expressions of HDAC1 in AS fibroblasts transfected with AAV-HDAC1 after DKK-1 and SIS3 treatment were detected by western blot analysis. E Densitometry analysis of protein expression. F Gene expressions of HDAC1 in AS fibroblasts were detected by RT-PCR analysis. Data were shown as mean ± SD. *P < 0.05, **P < 0.01 and ***P < 0.001, compared with the AAV-NC group. #P < 0.05, ##P < 0.01 and ###P < 0.001, compared with the AAV-HDAC1 group. &P < 0.05, &&P < 0.01 and &&&P < 0.001, compared with the AAV-HDAC1 + DKK-1 group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X