Fig. 4

A Bacterial enumeration of S. aureus (UAMS-1) in bone tissue (log CFU/g). B Bacterial enumeration of S. aureus (UAMS-1) on removed hardware implant (log CFU/g). Median ± interquartile range represented, and significance determined between groups using Kruskall-Wallis test followed by Dunn's multiple comparisons test, *p < 0.05. Group descriptions: SI (−): Saline irrigant; SI (+): Saline irrigant plus local antibiotic; ABI (+): Antibiofilm irrigant plus local antibiotic. All groups received systemic antibiotic