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Table 1 GO analysis of p16, p53, pcna, and co-expressed genes

From: Prognostic value of p16, p53, and pcna in sarcoma and an evaluation of immune infiltration

The enriched GO-ID Description Count P Value Genes
BP 0,046,104 Thymidine metabolic process 2 0.00380782 tk2, tk1
BP 0,007,265 Ras protein signal transduction 3 0.007837465 cdkn2a, tp53, mapkapk3
BP 0,048,010 Vascular endothelial growth factor receptor signaling pathway 3 0.00827545 nck2, ccl2, mapkapk3
BP 0,009,157 Deoxyribonucleoside monophosphate biosynthetic process 2 0.009493227 tk2, tk1
BP 0,031,497 Chromatin assembly 2 0.015147194 tp53, chaf1a
BP 0,043,065 Positive regulation of apoptotic process 4 0.019103663 hip1r, cdkn2a, tp53, nr4a1
BP 0,007,165 Signal transduction 7 0.020711051 nck2, tle2, tyrobp, ccl2, gdf15, mapkapk3, nr4a1
BP 0,016,925 Protein sumoylation 3 0.020834415 cdkn2a, pcna, tp53
BP 0,090,399 Replicative senescence 2 0.022637202 cdkn2a, tp53
BP 0,043,097 Pyrimidine nucleoside salvage 2 0.022637202 tk2, tk1
BP 0,009,165 Nucleotide biosynthetic process 2 0.028218465 tk2, tk1
BP 0,006,260 DNA replication 3 0.035043323 pcna, rfc2, chaf1a
BP 0,042,276 Error-prone translesion synthesis 2 0.035612139 pcna, rfc2
BP 0,070,987 Error-free translesion synthesis 2 0.035612139 pcna, rfc2
BP 0,006,297 Nucleotide-excision repair, DNA gap filling 2 0.044777623 pcna, rfc2
BP 0,071,158 Positive regulation of cell cycle arrest 2 0.046600567 cdkn2a, tp53
BP 0,007,507 Heart development 3 0.047320182 acan, pcna, cacna1c
BP 0,071,897 DNA biosynthetic process 2 0.04842014 tk2, tk1
CC 0,005,663 DNA replication factor C complex 2 0.010164404 pcna, rfc2
CC 0,016,605 PML body 3 0.012026098 tp53, sp140, trim27
CC 0,005,654 Nucleoplasm 11 0.013931808 cdkn2a, tle2, flii, pcna, tp53, rfc2, sp140, trim27, mapkapk3, nr4a1, hist2h4a
CC 0,005,657 Replication fork 2 0.028540071 pcna, tp53
CC 0,032,839 Dendrite cytoplasm 2 0.030194119 hip1r, grik3
CC 0,043,234 Protein complex 4 0.032294565 cdkn2a, tp53, chaf1a, hist2h4a
MF 0,042,802 Identical protein binding 8 4.19E-04 s100a2, pcna, tp53, cbs, tyrobp, trim27, chaf1a, tk1
MF 0,004,797 Thymidine kinase activity 2 0.003787763 tk2, tk1
MF 0,005,515 Protein binding 25 0.006734124 s100a2, hip1r, tle2, rfc2, sp140, nr4a1, tk1, hist2h4a, acan, cacna1c, clc, cbs, gdf15, ap1g2, chaf1a, nck2, pcna, tp53, abcb9, cdkn2a, flii, tyrobp, atp6v1b2, trim27, mapkapk3
MF 0,019,206 Nucleoside kinase activity 2 0.018800305 tk2, tk1
MF 0,019,899 Enzyme binding 4 0.024733293 pcna, brox, gabrd, iqch
MF 0,003,677 DNA binding 8 0.034312324 cdkn2a, pcna, tp53,rfc2, sp140, trim27, neu2, hist2h4a