Study, year, country | Study design | Sample size (n, M/F) | Mean age (years (SD), CSI/control) | Average onset (CSI/control) | Study group (n, CSI/control) | CSI group protocol | Control group protocol | Outcomes | Follow-up |
---|---|---|---|---|---|---|---|---|---|
Rompe et al. (2009) Germany | RCT | 229 (67/162) | 50 (not reported)/ (46 (not reported)/ 47 (not reported)) | 11Â m/ (14Â m/15Â m) | 75/ (76/78) | 0.5% Mepivacainmixed with 1Â mL of Prednisolone 25Â mg | home training/ ESWT | 6-point Likert scale, NRS | 15Â m |
Nissen et al. (2018) Switzerland | RCT | 46 (7/39) | 56.6 (14.6)/ 59.6 (13.1) |  ≥ 1 m | 21/25 | 4 ml of 1% lidocaine and 1 ml of betamethasone | placebo: 5 ml of sterile saline solution | NRS, 5-point Likert scale, WOMAC, SF-12, Oswestry low back pain questionnaire | 6 m |
Brinks et al. (2011), Netherlands | RCT | 120 (28/92) | 57.7 (13.9)/ 54.8 (14.7) |  ≥ 1w | 60/60 | 40 mg of triamcinolone acetate combined with 1% or 2% lidocaine | usual care: analgesics | 7-point Likert scale, NRS, EQ-5D, WOMAC | 12 m |
Brennan et al. ( 2017), USA | RCT | 43 (6/37) | 70.1 (11.4)/ 61.3 (16.5) | not reported | 22 (25 hips)/ 21 (25 hips) | 2Â ml methylprednisolone acetate 40Â mg/ml; 4Â ml 1% lidocaine; 4Â ml 0.25% marcaine (10Â ml total) | dry needling | NRS, PSFS | 6w |
Ribeiro et al., (2016), Brazil | RCT | 18 (8/10) | 49.6 (11.66)/ 50 (17.8) |  ≥ 3 m | 9 (10 hips)/ 9 (10 hips) | 4 ml solution of 80 mg of triamcinolone hexacetonide | PRP | FEPS, HHS, WOMAC | 60d |
Begkas et al. (2020), GRC | RCT | 24 (6/18) | not reported |  ≥ 12w | 12/12 | 4 ml of methylprednisolone (40 mg/ml) | PRP | VAS, HHS | 24w |
Fitzpatrick et al. (2018), Australia | RCT | 80 (8/72) | 59.7(not reported)/ 60.3(not reported) |  ≥ 4 m | 40/40 | Celestone Chronodose with saline | PRP | mHHS, PASS | 12w |
Mellor et al. (2018), Australia | RCT | 204 (37/167) | 55.3 (9.4)/ (54.8 (8.1)/54.5 (9.1)) | 18Â m/ (24Â m/24Â m) | 66/ (69/69) | 1Â ml betamethasone (5.7Â mg/ml) or 1Â ml triamcinolone acetonide (40Â mg/ml) combined with 2Â ml bupivacaine or 1Â ml Marcaine | education plus exercise/ wait and see | NRS, VISA-G, PSFS, EQ-5D, PSEQ, PCS, PHQ-9, LHPQ, the Active Australia survey | 52w |