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Fig. 7 | Journal of Orthopaedic Surgery and Research

Fig. 7

From: Roxadustat promotes osteoblast differentiation and prevents estrogen deficiency-induced bone loss by stabilizing HIF-1α and activating the Wnt/β-catenin signaling pathway

Fig. 7

Inhibition of the Wnt/β-catenin signaling pathway attenuated roxadustat-promoted osteoblast differentiation. A ALP staining at day 7. B Alizarin Red S staining at day 14. C The protein expression levels of β-catenin and osteogenic markers in osteoblasts at day 4. Data are presented as the mean ± SD of three independent experiments; *P < 0.05, **P < 0.01, compared with the control group; #P < 0.05, ##P < 0.01, compared with the Roxadustat + DKK-1 group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X