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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: The protective effect of kirenol in osteoarthritis: an in vitro and in vivo study

Fig. 3

Effect of kirenol on IL-1β-induced extracellular matrix (ECM) degradation in chondrocytes. A, B The protein level of Col II, aggrecan, MMP-13 and ADAMTS5 production on chondrocytes treated as above were detected by ELISA. C RT-PCR results of mRNA expressions of aggrecan and collagen II. D The representative fluorescence image of collagen II with DAPI (nuclei); scale bar: 10 μm. E The fluorescence intensity of collagen II was quantified by Image J software. The data presented are the means ± S.D. *p < 0.05, and **p < 0.01, one-way AVOVA, n = 6

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