Fig. 4
From: MiR-206 improves intervertebral disk degeneration by targeting GJA1
upregulation of miR-206 reduced inflammation and inhibited apoptosis by targeting GJA1 in LPS-induced NP cells. NP cells were treated with PBS, LPS, LPS + mimics NC, LPS + miR-206 mimics, or LPS + miR-206 mimics + GJA1. A miR-206 expression was measured by RT-PCR. B–D The content of IL-1β, TNF-α, and IL-6 was evaluated by ELISA. E, F The NP cells apoptosis was detected by flow cytometry. **P < 0.01 versus control group, ##P < 0.01 versus LPS group, ^^P < 0.01 versus LPS + miR-206 mimics group